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Uninstalling a module
One of the substantial changes in Drupal 8 is the module disable and uninstall process. Previously, modules were first disabled and then uninstalled once disabled. This created a confusing process, which would disable its features, but not clean up any database schema changes. In Drupal 8, modules cannot just be disabled but must be uninstalled. This ensures that when a module is uninstalled it can safely be removed from the code base.
A module can only be uninstalled if it is not a dependency of another module or does not have a configuration item in use--such as a field type--which could disrupt the installation's integrity.
With a standard installation, the Comment module cannot be uninstalled until you delete all the Comment fields on the article content type. This is because the field type is in use.